Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MCA0221Conserved domain protein; Identified by similarity to GP:17135185. (191 aa)    
Predicted Functional Partners:
MCA2187
Identified by match to protein family HMM PF00245; Belongs to the alkaline phosphatase family.
  
 
 0.958
folE
GTP cyclohydrolase I; Identified by similarity to SP:Q54769; match to protein family HMM PF01227; match to protein family HMM TIGR00063.
    
 0.916
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.910
folE2
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
     
  0.900
MCA2527
Putative 6-pyruvoyl tetrahydropterin synthase; Identified by similarity to SP:Q46903; match to protein family HMM PF01242.
     
  0.900
MCA1132
Conserved hypothetical protein; Identified by similarity to GP:17131502.
  
     0.727
MCA2235
Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA00697.
  
    0.659
MCA2227
Hemagglutinin-related protein; Identified by similarity to OMNI:NTL01RSA0540; match to protein family HMM PF05594; match to protein family HMM PF05860; match to protein family HMM TIGR01901.
  
    0.651
MCA1001
Conserved hypothetical protein; Identified by similarity to GP:17135359; match to protein family HMM PF07883.
  
     0.647
MCA2226
Conserved hypothetical protein; Identified by similarity to GP:9946574; match to protein family HMM PF07244.
  
    0.600
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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