Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA0236Conserved hypothetical protein; Identified by similarity to GP:12620458; match to protein family HMM PF03270. (152 aa)    
Predicted Functional Partners:
MCA0238
Ferredoxin, 4Fe-4S; Identified by similarity to SP:P46036; match to protein family HMM PF00037.
 
  
 0.979
nifE
Nitrogenase iron-molybdenum cofactor biosynthesis protein nifE; Identified by similarity to SP:P26506; match to protein family HMM PF00148; match to protein family HMM PF04324; match to protein family HMM TIGR01283; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.975
nifN
Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN; Identified by similarity to SP:P26507; match to protein family HMM PF00148; match to protein family HMM TIGR01285; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.968
MCA0235
Nitrogenase molybdenum-iron protein NifX; Identified by similarity to SP:P19078; match to protein family HMM PF02579.
    0.966
MCA0237
Conserved hypothetical protein; Identified by similarity to SP:Q44148; match to protein family HMM PF05082.
 
  
 0.946
nifK
Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.928
MCA0239
Putative nitrogen fixation protein nifQ; Identified by similarity to SP:P11068; match to protein family HMM PF04891.
 
    0.914
nifD
Nitrogenase molybdenum-iron protein alpha chain; Identified by similarity to SP:P06120; match to protein family HMM PF00148; match to protein family HMM TIGR01282; match to protein family HMM TIGR01862.
 
  
 0.907
MCA0232
Ferredoxin, 2Fe-2S; Identified by similarity to SP:P37097; match to protein family HMM PF00111.
 
  
 0.892
MCA0209
nifZ protein; Identified by similarity to SP:P08533; match to protein family HMM PF04319.
 
  
 0.852
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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