Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA0240Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA00760; match to protein family HMM PF01571; Belongs to the GcvT family. (356 aa)    
Predicted Functional Partners:
MCA0239
Putative nitrogen fixation protein nifQ; Identified by similarity to SP:P11068; match to protein family HMM PF04891.
     
 0.780
apaG
apaG protein; Identified by similarity to SP:Q56017; match to protein family HMM PF04379.
 
    0.697
erpA1
HesB/YadR/YfhF family protein; Required for insertion of 4Fe-4S clusters for at least IspG.
  
 
 0.632
erpA2
HesB/YadR/YfhF family protein; Required for insertion of 4Fe-4S clusters for at least IspG.
  
 
 0.629
MCA0238
Ferredoxin, 4Fe-4S; Identified by similarity to SP:P46036; match to protein family HMM PF00037.
       0.620
MCA0237
Conserved hypothetical protein; Identified by similarity to SP:Q44148; match to protein family HMM PF05082.
       0.607
clpP-1
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
   0.593
MCA0236
Conserved hypothetical protein; Identified by similarity to GP:12620458; match to protein family HMM PF03270.
       0.576
MCA0250
HesB/YadR/YfhF family protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.
  
 
 0.556
MCA0235
Nitrogenase molybdenum-iron protein NifX; Identified by similarity to SP:P19078; match to protein family HMM PF02579.
       0.554
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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