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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0262ATPase, AAA family; Identified by match to protein family HMM PF00004. (558 aa)    
Predicted Functional Partners:
MCA2199
Ankyrin repeat domain protein; Identified by match to protein family HMM PF00023.
   
 0.941
MCA0257
Conserved hypothetical protein; Identified by similarity to GP:17131609.
 
 
 
 0.861
MCA0207
Conserved hypothetical protein; Identified by similarity to GP:142364; match to protein family HMM PF00515; match to protein family HMM PF07719.
  
 
 
 0.779
gstB
Glutathione S-transferase; Identified by similarity to SP:P39100; match to protein family HMM PF02798.
 
 
   0.762
MCA0214
Conserved hypothetical protein; Identified by similarity to GP:551688.
  
     0.757
MCA2486
Identified by match to protein family HMM PF00850.
   
 0.745
MCA0222
Conserved hypothetical protein; Identified by similarity to GP:2983454.
 
     0.742
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.729
MCA2643
Conserved hypothetical protein; Identified by similarity to GP:17427847.
    
 0.728
htpG
Heat shock protein HtpG; Molecular chaperone. Has ATPase activity.
   
 0.712
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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