Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA0262ATPase, AAA family; Identified by match to protein family HMM PF00004. (558 aa)    
Predicted Functional Partners:
MCA2199
Ankyrin repeat domain protein; Identified by match to protein family HMM PF00023.
   
 0.920
MCA0257
Conserved hypothetical protein; Identified by similarity to GP:17131609.
 
 
  0.873
MCA2486
Identified by match to protein family HMM PF00850.
   
 0.841
MCA0207
Conserved hypothetical protein; Identified by similarity to GP:142364; match to protein family HMM PF00515; match to protein family HMM PF07719.
  
 
  0.795
gstB
Glutathione S-transferase; Identified by similarity to SP:P39100; match to protein family HMM PF02798.
 
 
   0.758
MCA0214
Conserved hypothetical protein; Identified by similarity to GP:551688.
  
     0.757
MCA0593
Identified by similarity to GP:4557191; match to protein family HMM PF00069; match to protein family HMM PF00481.
   
 
 0.754
MCA0222
Conserved hypothetical protein; Identified by similarity to GP:2983454.
 
     0.741
hepA
RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
    
 
 0.739
MCA2117
Rhodanese-like domain/ankyrin repeat domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
  
 
 0.700
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.