Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA0273Conserved domain protein. (49 aa)    
Predicted Functional Partners:
MCA0274
Putative type I restriction-modification system, R subunit; Identified by similarity to OMNI:NTL01XF02722; match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851.
  
    0.911
MCA0272
Type I restriction-modification system, S subunit domain protein.
  
    0.803
MCA0277
Conserved hypothetical protein; Identified by similarity to GP:9187842.
  
    0.761
MCA1889
Conserved hypothetical protein; Identified by similarity to GP:6723238.
  
    0.740
MCA0275
Identified by match to protein family HMM PF01381.
       0.730
MCA0276
Putative killer suppression protein HigA; Identified by similarity to GP:4098979.
       0.727
MCA0278
Type I restriction-modification system, M subunit; Identified by similarity to OMNI:NTL03PA02735; match to protein family HMM PF02384; match to protein family HMM PF02506.
  
   0.709
MCA1893
Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
  
    0.689
MCA0269
Conserved domain protein; Identified by similarity to OMNI:NTL02SA0423.
  
   0.631
MCA1890
Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420.
  
    0.551
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (14%) [HD]