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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0275Identified by match to protein family HMM PF01381. (386 aa)    
Predicted Functional Partners:
MCA0276
Putative killer suppression protein HigA; Identified by similarity to GP:4098979.
 
 
 
 0.992
MCA0274
Putative type I restriction-modification system, R subunit; Identified by similarity to OMNI:NTL01XF02722; match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851.
       0.812
MCA0273
Conserved domain protein.
       0.732
MCA0272
Type I restriction-modification system, S subunit domain protein.
       0.619
MCA0279
DNA binding domain, excisionase family; Identified by similarity to GP:2764916; match to protein family HMM TIGR01764.
  
  
 0.610
MCA0278
Type I restriction-modification system, M subunit; Identified by similarity to OMNI:NTL03PA02735; match to protein family HMM PF02384; match to protein family HMM PF02506.
       0.595
MCA0277
Conserved hypothetical protein; Identified by similarity to GP:9187842.
       0.592
MCA0269
Conserved domain protein; Identified by similarity to OMNI:NTL02SA0423.
       0.539
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
     
 0.461
vapC
Putative VagD protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
 
  
 0.454
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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