| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA0448 | MCA1322 | MCA0448 | MCA1322 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189. | 0.900 |
| MCA0448 | MCA1985 | MCA0448 | MCA1985 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | 0.904 |
| MCA0448 | MCA2982 | MCA0448 | MCA2982 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Hydrolase, haloacid dehalogenase-like family; Identified by similarity to OMNI:NTL03PA05178; match to protein family HMM PF00702; match to protein family HMM TIGR01509. | 0.910 |
| MCA0448 | MCA3023 | MCA0448 | MCA3023 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Ham1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.900 |
| MCA0448 | guaA | MCA0448 | MCA0290 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.932 |
| MCA0448 | guaB | MCA0448 | MCA0291 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.917 |
| MCA0448 | purA | MCA0448 | MCA1978 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.920 |
| MCA0448 | purB | MCA0448 | MCA1784 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.916 |
| MCA0448 | purH | MCA0448 | MCA1747 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. | 0.915 |
| MCA0448 | surE | MCA0448 | MCA2418 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
| MCA1322 | MCA0448 | MCA1322 | MCA0448 | 5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189. | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | 0.900 |
| MCA1322 | MCA1985 | MCA1322 | MCA1985 | 5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189. | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | 0.900 |
| MCA1322 | MCA2982 | MCA1322 | MCA2982 | 5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189. | Hydrolase, haloacid dehalogenase-like family; Identified by similarity to OMNI:NTL03PA05178; match to protein family HMM PF00702; match to protein family HMM TIGR01509. | 0.900 |
| MCA1322 | MCA3023 | MCA1322 | MCA3023 | 5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189. | Ham1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.900 |
| MCA1322 | guaA | MCA1322 | MCA0290 | 5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.900 |
| MCA1322 | guaB | MCA1322 | MCA0291 | 5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.900 |
| MCA1322 | purA | MCA1322 | MCA1978 | 5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.900 |
| MCA1322 | purB | MCA1322 | MCA1784 | 5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189. | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.900 |
| MCA1322 | purH | MCA1322 | MCA1747 | 5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. | 0.900 |
| MCA1322 | surE | MCA1322 | MCA2418 | 5'-nucleotidase; Identified by similarity to GP:12659324; match to protein family HMM PF06189. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
STRING v12.5 is now available!
