Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pmoC3Methane monooxygenase, C subunit; Identified by similarity to GP:14456716; match to protein family HMM PF04896. (253 aa)    
Predicted Functional Partners:
pmoB
Methane monooxygenase, B subunit; Methane monooxygenase is responsible for the initial oxygenation of methane to methanol in methanotrophs. At least in vitro, specific quinols can replace NADH as reductants.
   
 0.998
pmoA
Methane monooxygenase, A subunit; Non-catalytic subunit of the methane monooxygenase that is responsible for the initial oxygenation of methane to methanol in methanotrophs. At least in vitro, specific quinols can replace NADH as reductants.
   
 0.998
pmoC1
Methane monooxygenase, C subunit; Identified by similarity to GP:1894818; match to protein family HMM PF04896.
    
0.989
pmoB2
Methane monooxygenase, B subunit; Identified by similarity to GP:1913913; match to protein family HMM PF04744.
   
 
 0.956
mmoZ
Methane monooxygenase, A subunit, gamma chain; Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.
     
 0.955
pmoA2
Methane monooxygenase, A subunit; Identified by similarity to GP:1913912; match to protein family HMM PF02461.
   
 
 0.955
mmoX
Methane monooxygenase, A subunit, alpha chain; Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds; Belongs to the TmoA/XamoA family.
     
 0.947
nirD
Nitrite reductase [NAD(P)H], small subunit; Identified by similarity to SP:P42436; match to protein family HMM PF00355; match to protein family HMM TIGR02378.
     
 0.944
mmoB
Methane monooxygenase, B subunit; The B protein acts as a regulator of electron flow through the soluble mmo complex, switching the enzyme from an oxidase to a hydroxylase in the presence of the substrate; Belongs to the TmoD/XamoD family.
     
 0.940
gluD
Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P80053; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.938
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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