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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0299Putative methanol dehydrogenase protein, large subunit; Identified by similarity to SP:P15279; match to protein family HMM PF01011. (619 aa)    
Predicted Functional Partners:
MCA2778
Formaldehyde-activating enzyme domain protein; Identified by similarity to GP:11193064.
  
  
 0.922
mxaI
Methanol dehydrogenase, small subunit; Catalyzes the oxidation of primary alcohols including methanol.
 
 
 
 0.921
pmoC3
Methane monooxygenase, C subunit; Identified by similarity to GP:14456716; match to protein family HMM PF04896.
     
 0.911
pmoC1
Methane monooxygenase, C subunit; Identified by similarity to GP:1894818; match to protein family HMM PF04896.
     
 0.911
MCA2866
Formaldehyde-activating enzyme; Identified by similarity to GP:11193064.
     
 0.909
mmoX
Methane monooxygenase, A subunit, alpha chain; Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds; Belongs to the TmoA/XamoA family.
     
  0.900
mmoY
Methane monooxygenase, A subunit, beta chain; Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.
     
  0.900
mmoB
Methane monooxygenase, B subunit; The B protein acts as a regulator of electron flow through the soluble mmo complex, switching the enzyme from an oxidase to a hydroxylase in the presence of the substrate; Belongs to the TmoD/XamoD family.
     
  0.900
mmoZ
Methane monooxygenase, A subunit, gamma chain; Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.
     
  0.900
mmoD
Methane monooxygenase, D subunit.
     
  0.900
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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