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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0323Conserved domain protein; Identified by similarity to GP:17429805. (203 aa)    
Predicted Functional Partners:
mrcA
Penicillin-binding protein 1A; Identified by similarity to SP:P02918; match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074.
       0.771
pilO
Type 4 fimbrial biogenesis protein PilO; Identified by similarity to OMNI:NTL03PA05043; match to protein family HMM PF04350.
 
     0.672
pilN
Type 4 fimbrial biogenesis protein PilN; Identified by similarity to OMNI:NTL03PA05044; match to protein family HMM PF05137.
 
     0.668
pilP
Type 4 fimbrial biogenesis protein PilP; Identified by similarity to OMNI:NTL03PA05042; match to protein family HMM PF04351.
 
     0.636
pilQ
Fimbrial assembly protein PilQ; Identified by similarity to SP:P34750; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515.
 
     0.629
MCA0665
Putative glycine cleavage system transcriptional repressor; Identified by similarity to SP:P23483.
  
     0.620
MCA2596
HNH endonuclease domain protein; Identified by similarity to OMNI:NTL01XF01913; match to protein family HMM PF01844.
  
     0.613
pfp
Putative 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade [...]
  
 
 0.612
pilM
Type 4 fimbrial biogenesis protein PilM; Identified by similarity to OMNI:NTL03PA05045; match to protein family HMM TIGR01175.
 
     0.605
MCA2601
Identified by similarity to GP:4008541; match to protein family HMM PF03372.
  
     0.587
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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