| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA0333 | aroB | MCA0333 | MCA0331 | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.682 |
| MCA0333 | aroK | MCA0333 | MCA0330 | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.682 |
| MCA0333 | birA | MCA0333 | MCA1781 | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.664 |
| MCA0333 | hemE | MCA0333 | MCA0332 | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.773 |
| MCA0333 | nnrD | MCA0333 | MCA1301 | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.753 |
| MCA0333 | pilM | MCA0333 | MCA0325 | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | Type 4 fimbrial biogenesis protein PilM; Identified by similarity to OMNI:NTL03PA05045; match to protein family HMM TIGR01175. | 0.523 |
| MCA0333 | pilN | MCA0333 | MCA0326 | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | Type 4 fimbrial biogenesis protein PilN; Identified by similarity to OMNI:NTL03PA05044; match to protein family HMM PF05137. | 0.523 |
| MCA0333 | pilO | MCA0333 | MCA0327 | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | Type 4 fimbrial biogenesis protein PilO; Identified by similarity to OMNI:NTL03PA05043; match to protein family HMM PF04350. | 0.523 |
| MCA0333 | pilP | MCA0333 | MCA0328 | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | Type 4 fimbrial biogenesis protein PilP; Identified by similarity to OMNI:NTL03PA05042; match to protein family HMM PF04351. | 0.523 |
| MCA0333 | pilQ | MCA0333 | MCA0329 | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | Fimbrial assembly protein PilQ; Identified by similarity to SP:P34750; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515. | 0.523 |
| aroB | MCA0333 | MCA0331 | MCA0333 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | 0.682 |
| aroB | aroK | MCA0331 | MCA0330 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.999 |
| aroB | hemE | MCA0331 | MCA0332 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.758 |
| aroB | pilM | MCA0331 | MCA0325 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Type 4 fimbrial biogenesis protein PilM; Identified by similarity to OMNI:NTL03PA05045; match to protein family HMM TIGR01175. | 0.670 |
| aroB | pilN | MCA0331 | MCA0326 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Type 4 fimbrial biogenesis protein PilN; Identified by similarity to OMNI:NTL03PA05044; match to protein family HMM PF05137. | 0.679 |
| aroB | pilO | MCA0331 | MCA0327 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Type 4 fimbrial biogenesis protein PilO; Identified by similarity to OMNI:NTL03PA05043; match to protein family HMM PF04350. | 0.670 |
| aroB | pilP | MCA0331 | MCA0328 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Type 4 fimbrial biogenesis protein PilP; Identified by similarity to OMNI:NTL03PA05042; match to protein family HMM PF04351. | 0.673 |
| aroB | pilQ | MCA0331 | MCA0329 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Fimbrial assembly protein PilQ; Identified by similarity to SP:P34750; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515. | 0.713 |
| aroK | MCA0333 | MCA0330 | MCA0333 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | MutT/nudix family protein; Identified by similarity to OMNI:MT1739; match to protein family HMM PF00293. | 0.682 |
| aroK | aroB | MCA0330 | MCA0331 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.999 |
