Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gloBMetallo-beta-lactamase family protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (256 aa)    
Predicted Functional Partners:
gloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
 
 0.967
MCA0660
Identified by match to protein family HMM PF00753.
  
  
0.917
MCA0342
Identified by match to protein family HMM PF00488.
       0.773
MCA0341
Hypothetical protein; Identified by Glimmer2; putative.
       0.513
MCA3004
Pyridine nucleotide-disulphide oxidoreductase family protein; Identified by match to protein family HMM PF00070; match to protein family HMM PF00581; match to protein family HMM PF02852; match to protein family HMM PF07992.
  
 0.497
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
   
  
 0.472
gshB
Glutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family.
      
 0.470
gshA
Glutamate--cysteine ligase; Identified by similarity to SP:P06980; match to protein family HMM PF04262; match to protein family HMM TIGR01434; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
   
  
 0.453
rnhA
RNase H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.425
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
     
 0.419
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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