Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCA0381Hydrolase, carbon-nitrogen family; Identified by similarity to OMNI:NTL01NM01917; match to protein family HMM PF00795. (273 aa)    
Predicted Functional Partners:
pmbA
pmbA protein; Identified by similarity to SP:P24231; match to protein family HMM PF01523.
  
    0.761
MCA0380
Conserved hypothetical protein; Identified by similarity to OMNI:NTL02EC4081; match to protein family HMM TIGR02099.
 
     0.747
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
  
 0.744
tldD
tldD protein; Identified by similarity to SP:P46473; match to protein family HMM PF01523.
  
    0.718
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
  0.549
cafA
Ribonuclease G; Identified by similarity to SP:P25537; match to protein family HMM PF00575; match to protein family HMM TIGR00757.
       0.537
rlmH
Conserved hypothetical protein TIGR00246; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.532
maf-1
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.532
MCA1862
Hydrolase, carbon-nitrogen family; Identified by match to protein family HMM PF00795.
 
   
0.507
nadA
Quinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
     
 0.448
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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