STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0414Conserved hypothetical protein; Identified by similarity to SP:P45806; match to protein family HMM PF07119. (105 aa)    
Predicted Functional Partners:
MCA0415
TPR domain protein; Identified by similarity to OMNI:NTL03PA01484; match to protein family HMM PF00515; match to protein family HMM PF07719.
       0.522
ccmH
Cytochrome c-type biogenesis protein CcmH; Possible subunit of a heme lyase.
       0.522
dsbE-1
Thiol:disulfide interchange protein DsbE; Identified by similarity to SP:P33926; match to protein family HMM TIGR00385.
       0.522
ccmF
Cytochrome c-type biogenesis protein CcmF; Identified by similarity to SP:P33927; match to protein family HMM PF01578; match to protein family HMM TIGR00353.
       0.522
ccmE
Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
       0.522
MCA0420
Putative heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
       0.522
MCA0413
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SM00917; match to protein family HMM PF02622; Belongs to the UPF0301 (AlgH) family.
       0.516
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.