Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MCA0435Conserved hypothetical protein; Identified by similarity to OMNI:VC1548. (223 aa)    
Predicted Functional Partners:
MCA0436
MotA/TolQ/ExbB proton channel family protein; Identified by match to protein family HMM PF01618.
    0.990
exbB2
MotA/TolQ/ExbB proton channel family domain protein; Identified by match to protein family HMM PF01618.
 
    0.948
MCA0438
Biopolymer transport protein, ExbD/TolR family; Identified by similarity to SP:Q05606; match to protein family HMM PF02472.
 
     0.927
MCA0439
TonB domain protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
     0.858
MCA0474
ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.
  
 
 0.757
MCA0520
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.657
dsbE-2
Thiol:disulfide interchange protein DsbE; Identified by similarity to SP:P33926; match to protein family HMM TIGR00385.
   
   0.614
hepA
RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
  
 
 0.598
scpA
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.583
MCA0288
Transglycosylase SLT domain protein; Identified by match to protein family HMM PF01464.
  
     0.430
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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