STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0435Conserved hypothetical protein; Identified by similarity to OMNI:VC1548. (223 aa)    
Predicted Functional Partners:
MCA0436
MotA/TolQ/ExbB proton channel family protein; Identified by match to protein family HMM PF01618.
    0.990
exbB2
MotA/TolQ/ExbB proton channel family domain protein; Identified by match to protein family HMM PF01618.
 
    0.947
MCA0438
Biopolymer transport protein, ExbD/TolR family; Identified by similarity to SP:Q05606; match to protein family HMM PF02472.
 
     0.927
MCA0439
TonB domain protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
     0.855
scpA
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.734
MCA0520
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.657
dsbE-2
Thiol:disulfide interchange protein DsbE; Identified by similarity to SP:P33926; match to protein family HMM TIGR00385.
       0.608
MCA0474
ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.
  
 
 0.575
polI
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.505
MCA0288
Transglycosylase SLT domain protein; Identified by match to protein family HMM PF01464.
  
     0.430
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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