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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0439TonB domain protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (215 aa)    
Predicted Functional Partners:
MCA0438
Biopolymer transport protein, ExbD/TolR family; Identified by similarity to SP:Q05606; match to protein family HMM PF02472.
 
 
 0.919
MCA0436
MotA/TolQ/ExbB proton channel family protein; Identified by match to protein family HMM PF01618.
 
 
 0.914
exbB2
MotA/TolQ/ExbB proton channel family domain protein; Identified by match to protein family HMM PF01618.
 
 
 0.883
MCA0435
Conserved hypothetical protein; Identified by similarity to OMNI:VC1548.
 
     0.855
MCA2180
Putative TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
 
 
 0.720
MCA2074
TonB domain protein; Identified by similarity to SP:P76115; match to protein family HMM PF00593; match to protein family HMM PF07715.
  
 
 0.632
tolR
tolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.613
MCA0669
MotA/TolQ/ExbB proton channel family protein; Identified by similarity to OMNI:NTL03PA00199; match to protein family HMM PF01618.
 
 
 0.601
MCA1957
Putative TonB-dependent receptor; Identified by similarity to OMNI:CC1750; match to protein family HMM PF00593; match to protein family HMM PF07715.
 
 
 
 0.601
MCA0443
Biopolymer transport protein, ExbD/TolR family; Identified by similarity to SP:P05829; match to protein family HMM PF02472.
  
 
 0.599
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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