Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
MCA0439TonB domain protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (215 aa)    
Predicted Functional Partners:
MCA0438
Biopolymer transport protein, ExbD/TolR family; Identified by similarity to SP:Q05606; match to protein family HMM PF02472.
 
 
 0.921
MCA0436
MotA/TolQ/ExbB proton channel family protein; Identified by match to protein family HMM PF01618.
 
 
 0.914
exbB2
MotA/TolQ/ExbB proton channel family domain protein; Identified by match to protein family HMM PF01618.
 
 
 0.883
MCA0435
Conserved hypothetical protein; Identified by similarity to OMNI:VC1548.
 
     0.858
MCA2180
Putative TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
 
 
 0.745
MCA0669
MotA/TolQ/ExbB proton channel family protein; Identified by similarity to OMNI:NTL03PA00199; match to protein family HMM PF01618.
 
 
 0.728
MCA0442
MotA/TolQ/ExbB proton channel family protein; Identified by similarity to OMNI:NTL03PA00199; match to protein family HMM PF01618.
 
 
 0.713
MCA1957
Putative TonB-dependent receptor; Identified by similarity to OMNI:CC1750; match to protein family HMM PF00593; match to protein family HMM PF07715.
 
 
 
 0.687
MCA2074
TonB domain protein; Identified by similarity to SP:P76115; match to protein family HMM PF00593; match to protein family HMM PF07715.
  
 
 0.677
tolQ
tolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.676
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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