close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0447Sigma-54 dependent DNA-binding response regulator; Identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199. (313 aa)    
Predicted Functional Partners:
MCA3100
Response regulator; Identified by match to protein family HMM PF00072.
 
      0.819
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.786
MCA0831
Chemotaxis protein; Identified by similarity to SP:P18769; match to protein family HMM PF00072; match to protein family HMM PF01627; match to protein family HMM PF02518.
  
 
 0.757
MCA0446
Hypothetical protein; Identified by Glimmer2; putative.
       0.658
MCA1204
Sensory box histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM TIGR00229.
  
 
 0.628
MCA0445
Hypothetical protein; Identified by Glimmer2; putative.
       0.534
MCA1246
Putative methyltransferase CheR; Identified by match to protein family HMM PF00563; match to protein family HMM PF00785; match to protein family HMM PF00990; match to protein family HMM PF01739; match to protein family HMM PF03705; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254.
  
 
 0.473
ntrB
Nitrogen regulation protein NR(II); Identified by similarity to SP:P06712; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM TIGR00229.
 
 
 0.472
MCA0769
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by similarity to SP:P52647; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM PF02775; match to protein family HMM TIGR02176.
     
 0.465
MCA0453
Identified by match to protein family HMM PF01656.
  
 
 0.420
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.