Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCA0447Sigma-54 dependent DNA-binding response regulator; Identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199. (313 aa)    
Predicted Functional Partners:
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.903
MCA3100
Response regulator; Identified by match to protein family HMM PF00072.
 
      0.819
MCA0446
Hypothetical protein; Identified by Glimmer2; putative.
       0.658
mopB
Outer membrane protein MopB; Identified by similarity to GP:4104020; match to protein family HMM PF00691; match to protein family HMM PF02412.
   
  
 0.623
MCA0421
Cytochrome c5530 family protein.
      
 0.618
MCA0427
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.618
MCA0440
Putative TonB-dependent receptor; Identified by similarity to OMNI:NTL03PA03268; match to protein family HMM PF00593; match to protein family HMM PF07715.
      
 0.618
MCA0879
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
      
 0.618
MCA1185
Cytochrome c family protein; Identified by similarity to OMNI:NTL03PA02482; match to protein family HMM PF00034.
      
 0.618
MCA1186
Putative membrane protein.
      
 0.618
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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