| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA0448 | MCA1717 | MCA0448 | MCA1717 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Glycosyl transferase; Identified by match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831. | 0.911 |
| MCA0448 | apt | MCA0448 | MCA0816 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.922 |
| MCA0448 | cpdA | MCA0448 | MCA2085 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.916 |
| MCA0448 | guaA | MCA0448 | MCA0290 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.932 |
| MCA0448 | guaB | MCA0448 | MCA0291 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.917 |
| MCA0448 | purA | MCA0448 | MCA1978 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.920 |
| MCA0448 | purB | MCA0448 | MCA1784 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.916 |
| MCA0448 | purH | MCA0448 | MCA1747 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. | 0.915 |
| MCA0448 | surE | MCA0448 | MCA2418 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
| MCA0448 | tmk | MCA0448 | MCA1996 | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.925 |
| MCA1717 | MCA0448 | MCA1717 | MCA0448 | Glycosyl transferase; Identified by match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831. | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | 0.911 |
| MCA1717 | apt | MCA1717 | MCA0816 | Glycosyl transferase; Identified by match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.409 |
| MCA1717 | guaA | MCA1717 | MCA0290 | Glycosyl transferase; Identified by match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.508 |
| MCA1717 | surE | MCA1717 | MCA2418 | Glycosyl transferase; Identified by match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.930 |
| apt | MCA0448 | MCA0816 | MCA0448 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-nucleotidase family protein; Identified by similarity to OMNI:DR0505; match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | 0.922 |
| apt | MCA1717 | MCA0816 | MCA1717 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glycosyl transferase; Identified by match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831. | 0.409 |
| apt | cpdA | MCA0816 | MCA2085 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.901 |
| apt | guaA | MCA0816 | MCA0290 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.991 |
| apt | guaB | MCA0816 | MCA0291 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.570 |
| apt | purA | MCA0816 | MCA1978 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.568 |
STRING v12.5 is now available!
