Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MCA0460Ferredoxin, 4Fe-4S; Identified by similarity to GP:1518927; match to protein family HMM PF00037. (87 aa)    
Predicted Functional Partners:
MCA0459
Hypothetical protein; Identified by Glimmer2; putative.
       0.675
MCA0461
CBS/GGDEF/EAL domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00571; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
       0.541
MCA2577
Putative dehydrogenase subunit; Identified by similarity to GP:4007678; match to protein family HMM PF01257; match to protein family HMM PF01512.
   
 
 0.524
MCA2724
NAD-reducing hydrogenase, alpha subunit; Identified by similarity to SP:P22317; match to protein family HMM PF01257; match to protein family HMM PF01512.
   
 
 0.524
nuoE
NADH dehydrogenase I, E subunit; Identified by similarity to SP:P33601; match to protein family HMM PF01257; match to protein family HMM TIGR01958.
   
 
 0.466
MCA1393
Formate dehydrogenase, gamma subunit; Identified by similarity to GP:3724143; match to protein family HMM PF01257.
   
 
 0.466
nuoCD
NADH dehydrogenase I, C/D subunits; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
    0.426
MCA0458
Putative cysteine rich repeat domain protein; Identified by match to protein family HMM PF00839.
       0.413
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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