Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA0461CBS/GGDEF/EAL domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00571; match to protein family HMM PF00990; match to protein family HMM TIGR00254. (594 aa)    
Predicted Functional Partners:
MCA1204
Sensory box histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF01627; match to protein family HMM PF02518; match to protein family HMM TIGR00229.
 
 0.824
MCA2070
Sensory box protein; Identified by match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF01966; match to protein family HMM TIGR00229; match to protein family HMM TIGR00277.
 
 
 
 0.732
MCA1581
Identified by match to protein family HMM PF00909.
 
      0.726
amt-1
Ammonium transporter; Identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836.
 
      0.577
MCA0460
Ferredoxin, 4Fe-4S; Identified by similarity to GP:1518927; match to protein family HMM PF00037.
       0.541
MCA0456
GGDEF family protein; Identified by similarity to OMNI:VCA0960; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
 
 
0.539
cobU
Bifunctional cobalamin biosynthesis protein CobU; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
       0.515
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
       0.515
MCA0464
Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by similarity to SP:P52086; match to protein family HMM PF00300.
       0.515
MCA0459
Hypothetical protein; Identified by Glimmer2; putative.
       0.478
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.