Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pxpAConserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (260 aa)    
Predicted Functional Partners:
MCA0478
Allophanate hydrolase, subunit 1; Identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370.
 
 0.999
MCA0477
Allophanate hydrolase, subunit 2; Identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724.
  
 0.998
ggt
Gamma-glutamyltranspeptidase; Identified by similarity to SP:P18956; match to protein family HMM PF01019; match to protein family HMM TIGR00066.
     
  0.900
gshA
Glutamate--cysteine ligase; Identified by similarity to SP:P06980; match to protein family HMM PF04262; match to protein family HMM TIGR01434; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
glnA
Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.
   
 
  0.802
gluD
Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P80053; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
  0.800
MCA1684
Conserved domain protein; Identified by similarity to GP:11830835; match to protein family HMM PF05088.
     
  0.800
gltD
Glutamate synthase, NADH/NADPH small subunit; Identified by similarity to GP:17429987; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317.
     
  0.800
MCA1131
Conserved hypothetical protein TIGR00486; Identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486.
    
 0.690
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (12%) [HD]