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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0485Oxidoreductase, aldo/keto reductase family; Identified by match to protein family HMM PF00248. (283 aa)    
Predicted Functional Partners:
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 0.791
MCA0486
Conserved hypothetical protein; Identified by similarity to OMNI:PSPTO5190.
       0.768
MCA0431
Flavodoxin domain protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
   
 
 0.715
mtnA
Initiation factor 2 subunit family protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
 
    0.592
MCA2788
Alcohol dehydrogenase, zinc-containing; Identified by similarity to GP:17132042; match to protein family HMM PF00107.
  
  
 0.538
polI
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.462
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
 
 0.435
MCA0041
Oxidoreductase, Gfo/Idh/MocA family; Identified by similarity to OMNI:NTL01BH3849; match to protein family HMM PF01408; match to protein family HMM PF02894.
  
 0.429
MCA0487
Hypothetical protein; Identified by Glimmer2; putative.
       0.427
MCA0945
Conserved hypothetical protein; Identified by similarity to SP:Q49116.
  
     0.410
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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