Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fchAMethenyltetrahydrofolate cyclohydrolase; Identified by similarity to SP:Q49135; match to protein family HMM PF04961. (207 aa)    
Predicted Functional Partners:
MCA0508
Methylenetetrahydromethanopterin dehydrogenase/methylenetetrahydrofolate dehydrogenase; Identified by similarity to SP:P55818.
 
  
 0.971
fhs
Formate--tetrahydrofolate ligase; Identified by similarity to SP:P21164; match to protein family HMM PF01268; Belongs to the formate--tetrahydrofolate ligase family.
    
 0.928
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.912
MCA2773
Identified by match to protein family HMM PF01812; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
    
  0.909
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355.
    
  0.901
MCA2873
Squalene cyclase family protein; Identified by similarity to GP:1098635; match to protein family HMM PF00432; match to protein family HMM TIGR01787.
 
      0.663
MCA0299
Putative methanol dehydrogenase protein, large subunit; Identified by similarity to SP:P15279; match to protein family HMM PF01011.
      
 0.618
prmA
Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
      
 0.618
groEL-2
Chaperonin, 60 kDa subunit; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
      
 0.618
mxaF
Methanol dehydrogenase protein, large subunit; Identified by similarity to SP:P16027; match to protein family HMM PF01011.
      
 0.582
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.