Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
nirBNitrite reductase [NAD(P)H], large subunit; Identified by similarity to SP:P42435; match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (820 aa)    
Predicted Functional Partners:
nasA
Nitrate reductase; Identified by similarity to SP:Q06457; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04324; match to protein family HMM PF04879; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
 0.999
nirD
Nitrite reductase [NAD(P)H], small subunit; Identified by similarity to SP:P42436; match to protein family HMM PF00355; match to protein family HMM TIGR02378.
 
 0.999
MCA0594
Putative nitrate transporter; Identified by similarity to SP:P46907; match to protein family HMM PF07690.
 
 
 0.993
nasT
Response regulator NasT; Identified by similarity to GP:619066; match to protein family HMM PF00072; match to protein family HMM PF03861.
 
  
 0.967
glnA
Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.
    
 0.963
MCA0956
Hydroxylamine oxydoreductase; Identified by similarity to SP:Q50925.
     
 0.960
MCA0589
Putative nitrate transporter; Identified by similarity to SP:P38043.
 
  
 0.930
nifD
Nitrogenase molybdenum-iron protein alpha chain; Identified by similarity to SP:P06120; match to protein family HMM PF00148; match to protein family HMM TIGR01282; match to protein family HMM TIGR01862.
     
 0.920
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
   
 
 0.914
gluD
Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P80053; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.908
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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