| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroQ | folA | MCA1044 | MCA2729 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.628 |
| aroQ | ftsE | MCA1044 | MCA0134 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | 0.663 |
| aroQ | minC | MCA1044 | MCA3066 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.625 |
| aroQ | recJ | MCA1044 | MCA0628 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | single-stranded-DNA-specific exonuclease RecJ; Identified by similarity to SP:P21893; match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. | 0.661 |
| aroQ | rpiB | MCA1044 | MCA0043 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Ribose 5-phosphate isomerase B; Identified by similarity to SP:P37351; match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120. | 0.618 |
| aroQ | rpoA | MCA1044 | MCA2347 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.668 |
| aroQ | rpoC | MCA1044 | MCA1067 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.663 |
| folA | aroQ | MCA2729 | MCA1044 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.628 |
| folA | ftsE | MCA2729 | MCA0134 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | 0.618 |
| folA | minC | MCA2729 | MCA3066 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.623 |
| folA | recJ | MCA2729 | MCA0628 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | single-stranded-DNA-specific exonuclease RecJ; Identified by similarity to SP:P21893; match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. | 0.626 |
| folA | rpiB | MCA2729 | MCA0043 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Ribose 5-phosphate isomerase B; Identified by similarity to SP:P37351; match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120. | 0.638 |
| folA | rpoA | MCA2729 | MCA2347 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.629 |
| folA | rpoC | MCA2729 | MCA1067 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.675 |
| ftsE | aroQ | MCA0134 | MCA1044 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.663 |
| ftsE | folA | MCA0134 | MCA2729 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.618 |
| ftsE | minC | MCA0134 | MCA3066 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.710 |
| ftsE | polI | MCA0134 | MCA2573 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.554 |
| ftsE | recJ | MCA0134 | MCA0628 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | single-stranded-DNA-specific exonuclease RecJ; Identified by similarity to SP:P21893; match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. | 0.683 |
| ftsE | rpiB | MCA0134 | MCA0043 | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | Ribose 5-phosphate isomerase B; Identified by similarity to SP:P37351; match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120. | 0.618 |