Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA0657CRISPR-associated helicase Cas3; Identified by similarity to OMNI:NTL01BH0337; match to protein family HMM PF00270; match to protein family HMM TIGR01587. (732 aa)    
Predicted Functional Partners:
MCA0656
CRISPR-associated protein, CT1134 family; Identified by match to protein family HMM TIGR01876.
   
 0.978
MCA0655
CRISPR-associated protein, CT1133 family; Identified by match to protein family HMM TIGR01863.
   
 0.937
cas4
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
  
 0.910
MCA0654
CRISPR-associated protein, TM1801 family; Identified by similarity to OMNI:NTL01SPL1236; match to protein family HMM PF05107; match to protein family HMM TIGR01595.
 
  
 0.910
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.909
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.907
MCA0933
CRISPR-associated protein, CT1975 family; Identified by similarity to GP:16504014; match to protein family HMM TIGR01869.
  
 
 0.762
MCA0932
CRISPR-associated protein, CT1976 family; Identified by similarity to OMNI:NTL01EC02697; match to protein family HMM TIGR01868.
  
 
 0.759
MCA0935
CRISPR-associated protein, CT1972 family; Identified by match to protein family HMM TIGR02547.
  
 
 0.647
MCA0658
Hypothetical protein; Identified by Glimmer2; putative.
       0.572
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (12%) [HD]