| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA0664 | MCA0665 | MCA0664 | MCA0665 | Antioxidant, AhpC/Tsa family; Identified by similarity to GP:17428331; match to protein family HMM PF00578. | Putative glycine cleavage system transcriptional repressor; Identified by similarity to SP:P23483. | 0.812 |
| MCA0664 | MCA0667 | MCA0664 | MCA0667 | Antioxidant, AhpC/Tsa family; Identified by similarity to GP:17428331; match to protein family HMM PF00578. | DedA family protein; Identified by similarity to SP:P09548; match to protein family HMM PF00597. | 0.497 |
| MCA0664 | uppP | MCA0664 | MCA0666 | Antioxidant, AhpC/Tsa family; Identified by similarity to GP:17428331; match to protein family HMM PF00578. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.534 |
| MCA0665 | MCA0664 | MCA0665 | MCA0664 | Putative glycine cleavage system transcriptional repressor; Identified by similarity to SP:P23483. | Antioxidant, AhpC/Tsa family; Identified by similarity to GP:17428331; match to protein family HMM PF00578. | 0.812 |
| MCA0665 | MCA0667 | MCA0665 | MCA0667 | Putative glycine cleavage system transcriptional repressor; Identified by similarity to SP:P23483. | DedA family protein; Identified by similarity to SP:P09548; match to protein family HMM PF00597. | 0.547 |
| MCA0665 | uppP | MCA0665 | MCA0666 | Putative glycine cleavage system transcriptional repressor; Identified by similarity to SP:P23483. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.586 |
| MCA0667 | MCA0664 | MCA0667 | MCA0664 | DedA family protein; Identified by similarity to SP:P09548; match to protein family HMM PF00597. | Antioxidant, AhpC/Tsa family; Identified by similarity to GP:17428331; match to protein family HMM PF00578. | 0.497 |
| MCA0667 | MCA0665 | MCA0667 | MCA0665 | DedA family protein; Identified by similarity to SP:P09548; match to protein family HMM PF00597. | Putative glycine cleavage system transcriptional repressor; Identified by similarity to SP:P23483. | 0.547 |
| MCA0667 | uppP | MCA0667 | MCA0666 | DedA family protein; Identified by similarity to SP:P09548; match to protein family HMM PF00597. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.744 |
| MCA1133 | MCA2985 | MCA1133 | MCA2985 | Putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; Identified by similarity to SP:P24235; match to protein family HMM PF00953. | PAP2 superfamily protein; Identified by match to protein family HMM PF01569. | 0.900 |
| MCA1133 | uppP | MCA1133 | MCA0666 | Putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; Identified by similarity to SP:P24235; match to protein family HMM PF00953. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.909 |
| MCA2305 | uppP | MCA2305 | MCA0666 | Identified by match to protein family HMM PF00753; match to protein family HMM PF07521. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.612 |
| MCA2985 | MCA1133 | MCA2985 | MCA1133 | PAP2 superfamily protein; Identified by match to protein family HMM PF01569. | Putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; Identified by similarity to SP:P24235; match to protein family HMM PF00953. | 0.900 |
| MCA2985 | mraY | MCA2985 | MCA2432 | PAP2 superfamily protein; Identified by match to protein family HMM PF01569. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.900 |
| MCA2985 | uppP | MCA2985 | MCA0666 | PAP2 superfamily protein; Identified by match to protein family HMM PF01569. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.914 |
| MCA2985 | uppS | MCA2985 | MCA0571 | PAP2 superfamily protein; Identified by match to protein family HMM PF01569. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.907 |
| glmU | murA | MCA0014 | MCA1965 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.959 |
| glmU | uppP | MCA0014 | MCA0666 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.492 |
| mraY | MCA2985 | MCA2432 | MCA2985 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | PAP2 superfamily protein; Identified by match to protein family HMM PF01569. | 0.900 |
| mraY | murA | MCA2432 | MCA1965 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.764 |