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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0796Tat (twin-arginine translocation) pathway signal sequence domain protein; Identified by match to protein family HMM PF05951; match to protein family HMM TIGR01409. (195 aa)    
Predicted Functional Partners:
MCA1003
Conserved hypothetical protein; Identified by similarity to OMNI:NTL02ML0419; match to protein family HMM PF01471.
 
     0.798
MCA1690
Penicillin-insensitive murein endopeptidase, truncation; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.
  
     0.748
MCA0660
Identified by match to protein family HMM PF00753.
  
    0.664
MCA0795
Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA00360.
       0.468
tpm
Thiopurine methyltransferase; Identified by similarity to SP:O86262; match to protein family HMM PF05724; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
       0.442
MCA0873
ATP-dependent protease La domain protein.
  
     0.442
MCA0412
LysM domain protein; Identified by similarity to SP:P40680; match to protein family HMM PF01476; match to protein family HMM PF03734; match to protein family HMM PF05036.
 
     0.434
mtnC
Hydrolase, haloacid dehalogenase-like family; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
       0.428
mtnD
Dioxygenase, ARD/ARD' family; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
       0.428
mtnB
Conserved hypothetical protein; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.
       0.428
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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