| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA0864 | obg | MCA0864 | MCA2248 | Conserved hypothetical protein; Identified by similarity to OMNI:VC2536; match to protein family HMM PF04751; Belongs to the UPF0307 family. | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.465 |
| MCA0864 | rluD | MCA0864 | MCA0972 | Conserved hypothetical protein; Identified by similarity to OMNI:VC2536; match to protein family HMM PF04751; Belongs to the UPF0307 family. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.755 |
| MCA0864 | rplC | MCA0864 | MCA2372 | Conserved hypothetical protein; Identified by similarity to OMNI:VC2536; match to protein family HMM PF04751; Belongs to the UPF0307 family. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.489 |
| MCA0864 | rplM | MCA0864 | MCA0904 | Conserved hypothetical protein; Identified by similarity to OMNI:VC2536; match to protein family HMM PF04751; Belongs to the UPF0307 family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.468 |
| MCA0864 | rplQ | MCA0864 | MCA2346 | Conserved hypothetical protein; Identified by similarity to OMNI:VC2536; match to protein family HMM PF04751; Belongs to the UPF0307 family. | Ribosomal protein L17; Identified by similarity to SP:P02416; match to protein family HMM PF01196; match to protein family HMM TIGR00059. | 0.465 |
| MCA0864 | rplU | MCA0864 | MCA2246 | Conserved hypothetical protein; Identified by similarity to OMNI:VC2536; match to protein family HMM PF04751; Belongs to the UPF0307 family. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.476 |
| MCA0864 | rsfS | MCA0864 | MCA2027 | Conserved hypothetical protein; Identified by similarity to OMNI:VC2536; match to protein family HMM PF04751; Belongs to the UPF0307 family. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.492 |
| MCA0973 | MCA0974 | MCA0973 | MCA0974 | Conserved hypothetical protein TIGR00726; Identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family. | Conserved domain protein; Identified by similarity to GP:17429246. | 0.733 |
| MCA0973 | rluD | MCA0973 | MCA0972 | Conserved hypothetical protein TIGR00726; Identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.914 |
| MCA0974 | MCA0973 | MCA0974 | MCA0973 | Conserved domain protein; Identified by similarity to GP:17429246. | Conserved hypothetical protein TIGR00726; Identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.733 |
| MCA0974 | rluD | MCA0974 | MCA0972 | Conserved domain protein; Identified by similarity to GP:17429246. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.735 |
| obg | MCA0864 | MCA2248 | MCA0864 | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Conserved hypothetical protein; Identified by similarity to OMNI:VC2536; match to protein family HMM PF04751; Belongs to the UPF0307 family. | 0.465 |
| obg | rluD | MCA2248 | MCA0972 | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.869 |
| obg | rplC | MCA2248 | MCA2372 | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.798 |
| obg | rplM | MCA2248 | MCA0904 | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.801 |
| obg | rplQ | MCA2248 | MCA2346 | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal protein L17; Identified by similarity to SP:P02416; match to protein family HMM PF01196; match to protein family HMM TIGR00059. | 0.832 |
| obg | rplU | MCA2248 | MCA2246 | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.973 |
| obg | rsfS | MCA2248 | MCA2027 | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.895 |
| obg | trmE | MCA2248 | MCA3038 | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.471 |
| rluD | MCA0864 | MCA0972 | MCA0864 | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Conserved hypothetical protein; Identified by similarity to OMNI:VC2536; match to protein family HMM PF04751; Belongs to the UPF0307 family. | 0.755 |
STRING v12.5 is now available!
