Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MCA0978Heavy metal efflux pump, CzcA family; Identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1021 aa)    
Predicted Functional Partners:
MCA0979
Putative transporter; Identified by similarity to SP:P77239; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.953
MCA2263
Putative heavy metal efflux pump membrane fusion protein; Identified by similarity to SP:P77239; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.814
MCA1297
Efflux transporter, RND family, MFP subunit; Identified by match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.806
MCA2719
Putative heavy metal efflux system protein; Identified by similarity to SP:P37973; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.793
MCA0977
Putative nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543.
  
    0.773
MCA2110
Outer membrane efflux protein; Identified by match to protein family HMM PF02321.
 
  
 0.741
MCA1766
Putative heavy metal efflux system protein; Identified by similarity to SP:P13510; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.730
MCA1936
Putative transporter; Identified by similarity to SP:P94176; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   0.630
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
     
 0.620
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
      
 0.618
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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