close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA0987Rieske 2Fe-2S family protein; Identified by similarity to GP:17942398; match to protein family HMM PF00355. (106 aa)    
Predicted Functional Partners:
MCA2776
Pyridine nucleotide-disulphide oxidoreductase family protein; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992.
 
 0.983
nirB
Nitrite reductase [NAD(P)H], large subunit; Identified by similarity to SP:P42435; match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.812
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
  
 0.800
MCA0988
NifU family protein; Identified by similarity to SP:P77310; match to protein family HMM PF01592; match to protein family HMM TIGR01994.
       0.794
sufD
FeS assembly protein SufD; Identified by similarity to SP:P77689; match to protein family HMM PF01458; match to protein family HMM TIGR01981.
 
     0.653
nifE
Nitrogenase iron-molybdenum cofactor biosynthesis protein nifE; Identified by similarity to SP:P26506; match to protein family HMM PF00148; match to protein family HMM PF04324; match to protein family HMM TIGR01283; Belongs to the NifD/NifK/NifE/NifN family.
  
 
 0.625
csdB
Selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
       0.609
sufC
FeS assembly ATPase SufC; Identified by similarity to OMNI:NTL01ST1368; match to protein family HMM PF00005; match to protein family HMM TIGR01978.
       0.599
sufB
FeS assembly protein SufB; Identified by similarity to SP:P77522; match to protein family HMM PF01458; match to protein family HMM TIGR01980.
       0.540
MCA0993
Identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738.
       0.476
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.