Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sufBFeS assembly protein SufB; Identified by similarity to SP:P77522; match to protein family HMM PF01458; match to protein family HMM TIGR01980. (481 aa)    
Predicted Functional Partners:
sufD
FeS assembly protein SufD; Identified by similarity to SP:P77689; match to protein family HMM PF01458; match to protein family HMM TIGR01981.
 
0.999
sufC
FeS assembly ATPase SufC; Identified by similarity to OMNI:NTL01ST1368; match to protein family HMM PF00005; match to protein family HMM TIGR01978.
 
 0.999
csdB
Selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
 
 0.998
MCA0988
NifU family protein; Identified by similarity to SP:P77310; match to protein family HMM PF01592; match to protein family HMM TIGR01994.
 
  
 0.891
MCA0993
Identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738.
 
   
 0.832
MCA1270
Conserved hypothetical protein; Identified by similarity to GP:9107113; match to protein family HMM PF01883.
 
   
 0.799
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
  
 0.666
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
   
  
 0.633
hscA
Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
      
 0.630
MCA0248
NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
  
 0.628
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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