Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA1019Conserved hypothetical protein; Identified by similarity to OMNI:NT01MC4376. (556 aa)    
Predicted Functional Partners:
MCA1018
ErfK/YbiS/YcfS/YnhG family protein; Identified by similarity to OMNI:NTL02SC5233; match to protein family HMM PF03734.
       0.548
hepA
RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
    
 
 0.519
dsrE
Intracellular sulfur oxidation protein DsrE; Identified by similarity to SP:O87896; match to protein family HMM PF02635.
  
     0.496
MCA1333
Intracellular sulfur oxidation protein DsrH; Identified by similarity to GP:3228384; match to protein family HMM PF04077.
  
     0.494
MCA1020
Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.
     
 0.480
MCA0538
Peptidase, M48 family; Identified by match to protein family HMM PF01435.
  
 
  0.474
MCA2643
Conserved hypothetical protein; Identified by similarity to GP:17427847.
   
 0.461
MCA1119
General secretory pathway protein J; Identified by similarity to SP:P31740; match to protein family HMM PF07963; match to protein family HMM TIGR02532.
  
     0.438
MCA0760
Ferredoxin, 2Fe-2S; Identified by similarity to SP:P16022; match to protein family HMM PF00111.
  
     0.431
htpX
Heat shock protein HtpX; Identified by similarity to SP:P23894; match to protein family HMM PF01435; match to protein family HMM PF06509; Belongs to the peptidase M48B family.
    
  0.406
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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