MCA1020 protein (Methylococcus capsulatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MCA1020

Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. (159 aa)

Predicted Functional Partners:

MCA3023

0.815

MCA2780

0.666

MCA2199

0.636

MCA2117

0.623

MCA1019

0.489

MCA0593

0.468

Your Current Organism:

Methylococcus capsulatus

NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
MCA0593	MCA1020	Identified by similarity to GP:4557191; match to protein family HMM PF00069; match to protein family HMM PF00481.	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	0.468
MCA0593	MCA2117	Identified by similarity to GP:4557191; match to protein family HMM PF00069; match to protein family HMM PF00481.	Rhodanese-like domain/ankyrin repeat domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.	0.545
MCA0593	MCA2199	Identified by similarity to GP:4557191; match to protein family HMM PF00069; match to protein family HMM PF00481.	Ankyrin repeat domain protein; Identified by match to protein family HMM PF00023.	0.608
MCA0593	MCA2780	Identified by similarity to GP:4557191; match to protein family HMM PF00069; match to protein family HMM PF00481.	Ankyrin repeat domain protein.	0.402
MCA1019	MCA1020	Conserved hypothetical protein; Identified by similarity to OMNI:NT01MC4376.	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	0.489
MCA1020	MCA0593	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	Identified by similarity to GP:4557191; match to protein family HMM PF00069; match to protein family HMM PF00481.	0.468
MCA1020	MCA1019	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	Conserved hypothetical protein; Identified by similarity to OMNI:NT01MC4376.	0.489
MCA1020	MCA2117	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	Rhodanese-like domain/ankyrin repeat domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.	0.623
MCA1020	MCA2199	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	Ankyrin repeat domain protein; Identified by match to protein family HMM PF00023.	0.636
MCA1020	MCA2780	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	Ankyrin repeat domain protein.	0.666
MCA1020	MCA3023	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	Ham1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.815
MCA2117	MCA0593	Rhodanese-like domain/ankyrin repeat domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.	Identified by similarity to GP:4557191; match to protein family HMM PF00069; match to protein family HMM PF00481.	0.545
MCA2117	MCA1020	Rhodanese-like domain/ankyrin repeat domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	0.623
MCA2117	MCA2199	Rhodanese-like domain/ankyrin repeat domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.	Ankyrin repeat domain protein; Identified by match to protein family HMM PF00023.	0.448
MCA2199	MCA0593	Ankyrin repeat domain protein; Identified by match to protein family HMM PF00023.	Identified by similarity to GP:4557191; match to protein family HMM PF00069; match to protein family HMM PF00481.	0.608
MCA2199	MCA1020	Ankyrin repeat domain protein; Identified by match to protein family HMM PF00023.	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	0.636
MCA2199	MCA2117	Ankyrin repeat domain protein; Identified by match to protein family HMM PF00023.	Rhodanese-like domain/ankyrin repeat domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.	0.448
MCA2780	MCA0593	Ankyrin repeat domain protein.	Identified by similarity to GP:4557191; match to protein family HMM PF00069; match to protein family HMM PF00481.	0.402
MCA2780	MCA1020	Ankyrin repeat domain protein.	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	0.666
MCA3023	MCA1020	Ham1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Putative phosphoesterase; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	0.815

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Textmining

Coexpression

Databases

Fusion

© STRING Consortium 2025

Credits

Access

Info

About