Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA1023Identified by match to protein family HMM PF00578. (201 aa)    
Predicted Functional Partners:
MCA0042
Antioxidant, AhpC/Tsa family; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.918
trxB
Thioredoxin-disulfide reductase; Identified by similarity to SP:P09625; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
  
 
 0.900
dsbE-1
Thiol:disulfide interchange protein DsbE; Identified by similarity to SP:P33926; match to protein family HMM TIGR00385.
  
 0.818
dsbE-2
Thiol:disulfide interchange protein DsbE; Identified by similarity to SP:P33926; match to protein family HMM TIGR00385.
  
 0.818
MCA1042
Thiol:disulfide interchange protein like protein.
  
 0.818
MCA0474
ATP-dependent DNA helicase, UvrD/REP family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00580; match to protein family HMM TIGR00614.
    
   0.797
fur
Ferric uptake regulation protein; Identified by similarity to SP:P06975; match to protein family HMM PF01475; Belongs to the Fur family.
  
  
 0.750
MCA0664
Antioxidant, AhpC/Tsa family; Identified by similarity to GP:17428331; match to protein family HMM PF00578.
 
 
 0.698
sodB-2
Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.687
bsaA
Glutathione peroxidase; Identified by similarity to SP:P52035; match to protein family HMM PF00255; Belongs to the glutathione peroxidase family.
    
 
 0.676
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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