Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA1168Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P32057; match to protein family HMM PF00534. (404 aa)    
Predicted Functional Partners:
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 0.936
MCA0147
Putative polysaccharide biosythesis protein; Identified by similarity to GP:4972659; match to protein family HMM PF02397.
  
 0.876
MCA1133
Putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; Identified by similarity to SP:P24235; match to protein family HMM PF00953.
 
  
 0.820
MCA1160
Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534.
 
    0.649
MCA1178
Putative exopolysaccharide export protein, interruption-C; This gene is interrupted by an IS element; identified by similarity to SP:Q45409.
 
  
 0.646
MCA2124
Putative colanic acid biosynthesis glycosyl transferase; Identified by similarity to SP:P71243; match to protein family HMM PF00534.
  
  
 0.642
MCA1437
Bacterial sugar transferase/glycosyl transferase, WecB/TagA/CpsF family protein; Identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696; Belongs to the glycosyltransferase 26 family.
  
 
 0.632
dnaK
dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 
 0.625
djlA
DnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
      
 0.618
MCA1166
Identified by similarity to GP:17132272; match to protein family HMM PF00535.
 
    0.584
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.