node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCA0464 | MCA1249 | MCA0464 | MCA1249 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by similarity to SP:P52086; match to protein family HMM PF00300. | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | 0.911 |
MCA0464 | cobQ | MCA0464 | MCA2304 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by similarity to SP:P52086; match to protein family HMM PF00300. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.537 |
MCA0464 | cobS | MCA0464 | MCA0465 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by similarity to SP:P52086; match to protein family HMM PF00300. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.993 |
MCA0464 | cobT | MCA0464 | MCA0463 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by similarity to SP:P52086; match to protein family HMM PF00300. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.992 |
MCA0464 | cobU | MCA0464 | MCA0462 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by similarity to SP:P52086; match to protein family HMM PF00300. | Bifunctional cobalamin biosynthesis protein CobU; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.943 |
MCA1249 | MCA0464 | MCA1249 | MCA0464 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by similarity to SP:P52086; match to protein family HMM PF00300. | 0.911 |
MCA1249 | argH | MCA1249 | MCA1248 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | Argininosuccinate lyase; Identified by similarity to SP:P50987; match to protein family HMM PF00206; match to protein family HMM TIGR00838. | 0.793 |
MCA1249 | cbbL | MCA1249 | MCA2743 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | Ribulose bisphosphate carboxylase, large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. | 0.499 |
MCA1249 | cobQ | MCA1249 | MCA2304 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.560 |
MCA1249 | cobS | MCA1249 | MCA0465 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.979 |
MCA1249 | cobT | MCA1249 | MCA0463 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.965 |
MCA1249 | cobU | MCA1249 | MCA0462 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | Bifunctional cobalamin biosynthesis protein CobU; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.733 |
MCA1249 | gap | MCA1249 | MCA2598 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | Glyceraldehyde 3-phosphate dehydrogenase; Identified by similarity to SP:P50321; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.566 |
MCA1249 | gpmA | MCA1249 | MCA0753 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. | 0.553 |
MCA1249 | pgi | MCA1249 | MCA1247 | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | Glucose-6-phosphate isomerase; Identified by similarity to SP:P11537; match to protein family HMM PF00342. | 0.598 |
argH | MCA1249 | MCA1248 | MCA1249 | Argininosuccinate lyase; Identified by similarity to SP:P50987; match to protein family HMM PF00206; match to protein family HMM TIGR00838. | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | 0.793 |
argH | pgi | MCA1248 | MCA1247 | Argininosuccinate lyase; Identified by similarity to SP:P50987; match to protein family HMM PF00206; match to protein family HMM TIGR00838. | Glucose-6-phosphate isomerase; Identified by similarity to SP:P11537; match to protein family HMM PF00342. | 0.653 |
cbbL | MCA1249 | MCA2743 | MCA1249 | Ribulose bisphosphate carboxylase, large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by match to protein family HMM PF00300. | 0.499 |
cbbL | gpmA | MCA2743 | MCA0753 | Ribulose bisphosphate carboxylase, large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. | 0.517 |
cobQ | MCA0464 | MCA2304 | MCA0464 | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Putative alpha-ribazole-5`-phosphate phosphatase CobC; Identified by similarity to SP:P52086; match to protein family HMM PF00300. | 0.537 |