node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCA1436 | cysE-1 | MCA1436 | MCA1830 | Putative serine acetyltransferase CysE; Identified by similarity to SP:P71405; match to protein family HMM PF00132. | Serine acetyltransferase; Identified by similarity to SP:P74089; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | 0.916 |
MCA1436 | cysE-2 | MCA1436 | MCA2611 | Putative serine acetyltransferase CysE; Identified by similarity to SP:P71405; match to protein family HMM PF00132. | Serine acetyltransferase; Identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172. | 0.918 |
MCA1436 | glyA | MCA1436 | MCA1660 | Putative serine acetyltransferase CysE; Identified by similarity to SP:P71405; match to protein family HMM PF00132. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.816 |
MCA1436 | ilvA | MCA1436 | MCA0354 | Putative serine acetyltransferase CysE; Identified by similarity to SP:P71405; match to protein family HMM PF00132. | Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.801 |
MCA1436 | pssA | MCA1436 | MCA2273 | Putative serine acetyltransferase CysE; Identified by similarity to SP:P71405; match to protein family HMM PF00132. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by similarity to SP:Q48269; match to protein family HMM PF01066; match to protein family HMM TIGR00473; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.800 |
MCA1436 | serB | MCA1436 | MCA1267 | Putative serine acetyltransferase CysE; Identified by similarity to SP:P71405; match to protein family HMM PF00132. | Phosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. | 0.817 |
MCA1436 | sgaA | MCA1436 | MCA1406 | Putative serine acetyltransferase CysE; Identified by similarity to SP:P71405; match to protein family HMM PF00132. | Serine--glyoxylate aminotransferase; Identified by similarity to SP:P55819; match to protein family HMM PF00266. | 0.800 |
MCA1436 | trpA | MCA1436 | MCA2494 | Putative serine acetyltransferase CysE; Identified by similarity to SP:P71405; match to protein family HMM PF00132. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.802 |
MCA1436 | trpB | MCA1436 | MCA2495 | Putative serine acetyltransferase CysE; Identified by similarity to SP:P71405; match to protein family HMM PF00132. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.801 |
cysE-1 | MCA1436 | MCA1830 | MCA1436 | Serine acetyltransferase; Identified by similarity to SP:P74089; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Putative serine acetyltransferase CysE; Identified by similarity to SP:P71405; match to protein family HMM PF00132. | 0.916 |
cysE-1 | cysE-2 | MCA1830 | MCA2611 | Serine acetyltransferase; Identified by similarity to SP:P74089; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Serine acetyltransferase; Identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172. | 0.904 |
cysE-1 | glyA | MCA1830 | MCA1660 | Serine acetyltransferase; Identified by similarity to SP:P74089; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.816 |
cysE-1 | ilvA | MCA1830 | MCA0354 | Serine acetyltransferase; Identified by similarity to SP:P74089; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.801 |
cysE-1 | pssA | MCA1830 | MCA2273 | Serine acetyltransferase; Identified by similarity to SP:P74089; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by similarity to SP:Q48269; match to protein family HMM PF01066; match to protein family HMM TIGR00473; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.800 |
cysE-1 | serB | MCA1830 | MCA1267 | Serine acetyltransferase; Identified by similarity to SP:P74089; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Phosphoserine phosphatase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. | 0.817 |
cysE-1 | sgaA | MCA1830 | MCA1406 | Serine acetyltransferase; Identified by similarity to SP:P74089; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Serine--glyoxylate aminotransferase; Identified by similarity to SP:P55819; match to protein family HMM PF00266. | 0.800 |
cysE-1 | trpA | MCA1830 | MCA2494 | Serine acetyltransferase; Identified by similarity to SP:P74089; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.802 |
cysE-1 | trpB | MCA1830 | MCA2495 | Serine acetyltransferase; Identified by similarity to SP:P74089; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.801 |
cysE-2 | MCA1436 | MCA2611 | MCA1436 | Serine acetyltransferase; Identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Putative serine acetyltransferase CysE; Identified by similarity to SP:P71405; match to protein family HMM PF00132. | 0.918 |
cysE-2 | cysE-1 | MCA2611 | MCA1830 | Serine acetyltransferase; Identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172. | Serine acetyltransferase; Identified by similarity to SP:P74089; match to protein family HMM PF00132; match to protein family HMM TIGR01172. | 0.904 |