node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCA1164 | MCA1754 | MCA1164 | MCA1754 | Methyltransferase domain protein. | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | 0.914 |
MCA1164 | ubiG | MCA1164 | MCA1272 | Methyltransferase domain protein. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.900 |
MCA1164 | ubiH | MCA1164 | MCA2769 | Methyltransferase domain protein. | 2-octaprenyl-6-methoxyphenol hydroxylase; Identified by similarity to SP:P25534; match to protein family HMM PF01360; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 0.914 |
MCA1270 | MCA1271 | MCA1270 | MCA1271 | Conserved hypothetical protein; Identified by similarity to GP:9107113; match to protein family HMM PF01883. | Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106. | 0.816 |
MCA1270 | mtaD | MCA1270 | MCA1273 | Conserved hypothetical protein; Identified by similarity to GP:9107113; match to protein family HMM PF01883. | Chlorohydrolase family protein; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.786 |
MCA1270 | ubiG | MCA1270 | MCA1272 | Conserved hypothetical protein; Identified by similarity to GP:9107113; match to protein family HMM PF01883. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.816 |
MCA1271 | MCA1270 | MCA1271 | MCA1270 | Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106. | Conserved hypothetical protein; Identified by similarity to GP:9107113; match to protein family HMM PF01883. | 0.816 |
MCA1271 | mtaD | MCA1271 | MCA1273 | Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106. | Chlorohydrolase family protein; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.790 |
MCA1271 | ubiG | MCA1271 | MCA1272 | Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.825 |
MCA1754 | MCA1164 | MCA1754 | MCA1164 | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | Methyltransferase domain protein. | 0.914 |
MCA1754 | ubiA | MCA1754 | MCA1336 | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.720 |
MCA1754 | ubiE | MCA1754 | MCA2017 | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | Ubiquinone/menaquinone biosynthesis methlytransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.928 |
MCA1754 | ubiG | MCA1754 | MCA1272 | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.960 |
gltA | ubiG | MCA0847 | MCA1272 | Citrate synthase; Identified by similarity to SP:Q10530; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.651 |
mtaD | MCA1270 | MCA1273 | MCA1270 | Chlorohydrolase family protein; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | Conserved hypothetical protein; Identified by similarity to GP:9107113; match to protein family HMM PF01883. | 0.786 |
mtaD | MCA1271 | MCA1273 | MCA1271 | Chlorohydrolase family protein; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106. | 0.790 |
mtaD | ubiG | MCA1273 | MCA1272 | Chlorohydrolase family protein; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.788 |
rrmJ | ubiG | MCA1849 | MCA1272 | Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.507 |
ubiA | MCA1754 | MCA1336 | MCA1754 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | 0.720 |
ubiA | ubiG | MCA1336 | MCA1272 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.707 |