| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA1684 | glnA | MCA1684 | MCA1677 | Conserved domain protein; Identified by similarity to GP:11830835; match to protein family HMM PF05088. | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.939 |
| MCA1684 | gltD | MCA1684 | MCA2040 | Conserved domain protein; Identified by similarity to GP:11830835; match to protein family HMM PF05088. | Glutamate synthase, NADH/NADPH small subunit; Identified by similarity to GP:17429987; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317. | 0.918 |
| MCA1684 | gluD | MCA1684 | MCA1030 | Conserved domain protein; Identified by similarity to GP:11830835; match to protein family HMM PF05088. | Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P80053; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.913 |
| MCA1684 | murI | MCA1684 | MCA1276 | Conserved domain protein; Identified by similarity to GP:11830835; match to protein family HMM PF05088. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.800 |
| MCA3023 | murI | MCA3023 | MCA1276 | Ham1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.919 |
| ald | murI | MCA0563 | MCA1276 | Alanine dehydrogenase; Identified by similarity to SP:P17556; match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.800 |
| ald | sgaA | MCA0563 | MCA1406 | Alanine dehydrogenase; Identified by similarity to SP:P17556; match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00518; Belongs to the AlaDH/PNT family. | Serine--glyoxylate aminotransferase; Identified by similarity to SP:P55819; match to protein family HMM PF00266. | 0.902 |
| glnA | MCA1684 | MCA1677 | MCA1684 | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | Conserved domain protein; Identified by similarity to GP:11830835; match to protein family HMM PF05088. | 0.939 |
| glnA | gltD | MCA1677 | MCA2040 | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | Glutamate synthase, NADH/NADPH small subunit; Identified by similarity to GP:17429987; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317. | 0.972 |
| glnA | gluD | MCA1677 | MCA1030 | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P80053; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.975 |
| glnA | murI | MCA1677 | MCA1276 | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.850 |
| gltD | MCA1684 | MCA2040 | MCA1684 | Glutamate synthase, NADH/NADPH small subunit; Identified by similarity to GP:17429987; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317. | Conserved domain protein; Identified by similarity to GP:11830835; match to protein family HMM PF05088. | 0.918 |
| gltD | glnA | MCA2040 | MCA1677 | Glutamate synthase, NADH/NADPH small subunit; Identified by similarity to GP:17429987; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317. | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.972 |
| gltD | gluD | MCA2040 | MCA1030 | Glutamate synthase, NADH/NADPH small subunit; Identified by similarity to GP:17429987; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317. | Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P80053; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.971 |
| gltD | murI | MCA2040 | MCA1276 | Glutamate synthase, NADH/NADPH small subunit; Identified by similarity to GP:17429987; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.800 |
| gluD | MCA1684 | MCA1030 | MCA1684 | Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P80053; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Conserved domain protein; Identified by similarity to GP:11830835; match to protein family HMM PF05088. | 0.913 |
| gluD | glnA | MCA1030 | MCA1677 | Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P80053; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.975 |
| gluD | gltD | MCA1030 | MCA2040 | Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P80053; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate synthase, NADH/NADPH small subunit; Identified by similarity to GP:17429987; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317. | 0.971 |
| gluD | murI | MCA1030 | MCA1276 | Glutamate dehydrogenase, NAD-specific; Identified by similarity to SP:P80053; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.838 |
| murC | murD | MCA2428 | MCA2431 | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.999 |