Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cddCytosine deaminase; Identified by similarity to SP:Q12178; match to protein family HMM PF00383. (145 aa)    
Predicted Functional Partners:
MCA3091
Decarboxylase family protein; Identified by similarity to OMNI:VC0899; match to protein family HMM PF03641.
    
  0.901
ppnP
Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
MCA1717
Glycosyl transferase; Identified by match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831.
     
  0.900
MCA2334
Putative pyrimidine operon regulatory protein PyrR; Identified by similarity to SP:P39765; match to protein family HMM PF00156.
     
  0.900
birA
birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.777
MCA1305
DnaK-related protein; Belongs to the heat shock protein 70 family.
   
   0.664
MCA1306
DnaK-related protein.
   
   0.664
MCA1304
Conserved hypothetical protein; Identified by similarity to OMNI:VC1375.
       0.655
MCA1498
Zinc-binding domain protein; Identified by match to protein family HMM PF00383.
  
     0.632
MCA1308
Conserved hypothetical protein; Identified by similarity to GP:16502260; match to protein family HMM PF01027; Belongs to the BI1 family.
       0.550
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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