| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA1325 | MCA1327 | MCA1325 | MCA1327 | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.779 |
| MCA1325 | cobB-2 | MCA1325 | MCA1627 | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | Transcriptional regulator, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | 0.457 |
| MCA1325 | dnaZX | MCA1325 | MCA1328 | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.750 |
| MCA1325 | glnA | MCA1325 | MCA1677 | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.792 |
| MCA1325 | hepA | MCA1325 | MCA2531 | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.515 |
| MCA1325 | recR | MCA1325 | MCA1326 | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.750 |
| MCA1327 | MCA1325 | MCA1327 | MCA1325 | Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | 0.779 |
| MCA1327 | dnaZX | MCA1327 | MCA1328 | Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.974 |
| MCA1327 | recR | MCA1327 | MCA1326 | Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.991 |
| cobB-2 | MCA1325 | MCA1627 | MCA1325 | Transcriptional regulator, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | 0.457 |
| dnaZX | MCA1325 | MCA1328 | MCA1325 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | 0.750 |
| dnaZX | MCA1327 | MCA1328 | MCA1327 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.974 |
| dnaZX | recR | MCA1328 | MCA1326 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.940 |
| glnA | MCA1325 | MCA1677 | MCA1325 | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | 0.792 |
| hepA | MCA1325 | MCA2531 | MCA1325 | RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | 0.515 |
| recR | MCA1325 | MCA1326 | MCA1325 | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | HIT family protein; Identified by similarity to GP:18145688; match to protein family HMM PF01230. | 0.750 |
| recR | MCA1327 | MCA1326 | MCA1327 | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.991 |
| recR | dnaZX | MCA1326 | MCA1328 | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.940 |
