| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA1495 | ubiA | MCA1495 | MCA1336 | Conserved hypothetical protein; Identified by similarity to GP:2624947. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.902 |
| MCA1495 | ubiC | MCA1495 | MCA1335 | Conserved hypothetical protein; Identified by similarity to GP:2624947. | Putative chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.905 |
| MCA1754 | MCA2078 | MCA1754 | MCA2078 | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | Glutaredoxin-related protein; Identified by similarity to GP:19880969; match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.463 |
| MCA1754 | ispB | MCA1754 | MCA2996 | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | Octaprenyl-diphosphate synthase; Identified by similarity to SP:P19641; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 0.430 |
| MCA1754 | ubiA | MCA1754 | MCA1336 | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.760 |
| MCA1754 | ubiG | MCA1754 | MCA1272 | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.972 |
| MCA1754 | ubiH | MCA1754 | MCA2769 | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | 2-octaprenyl-6-methoxyphenol hydroxylase; Identified by similarity to SP:P25534; match to protein family HMM PF01360; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 0.484 |
| MCA2078 | MCA1754 | MCA2078 | MCA1754 | Glutaredoxin-related protein; Identified by similarity to GP:19880969; match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | 0.463 |
| MCA2078 | ubiA | MCA2078 | MCA1336 | Glutaredoxin-related protein; Identified by similarity to GP:19880969; match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.917 |
| MCA2078 | ubiG | MCA2078 | MCA1272 | Glutaredoxin-related protein; Identified by similarity to GP:19880969; match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.406 |
| MCA2078 | ubiH | MCA2078 | MCA2769 | Glutaredoxin-related protein; Identified by similarity to GP:19880969; match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. | 2-octaprenyl-6-methoxyphenol hydroxylase; Identified by similarity to SP:P25534; match to protein family HMM PF01360; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 0.441 |
| dsrE | ubiA | MCA1331 | MCA1336 | Intracellular sulfur oxidation protein DsrE; Identified by similarity to SP:O87896; match to protein family HMM PF02635. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.478 |
| dsrE | ubiC | MCA1331 | MCA1335 | Intracellular sulfur oxidation protein DsrE; Identified by similarity to SP:O87896; match to protein family HMM PF02635. | Putative chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.569 |
| ispB | MCA1754 | MCA2996 | MCA1754 | Octaprenyl-diphosphate synthase; Identified by similarity to SP:P19641; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | 0.430 |
| ispB | ubiA | MCA2996 | MCA1336 | Octaprenyl-diphosphate synthase; Identified by similarity to SP:P19641; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.893 |
| ispB | ubiH | MCA2996 | MCA2769 | Octaprenyl-diphosphate synthase; Identified by similarity to SP:P19641; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 2-octaprenyl-6-methoxyphenol hydroxylase; Identified by similarity to SP:P25534; match to protein family HMM PF01360; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 0.433 |
| ubiA | MCA1495 | MCA1336 | MCA1495 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Conserved hypothetical protein; Identified by similarity to GP:2624947. | 0.902 |
| ubiA | MCA1754 | MCA1336 | MCA1754 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Monooxygenase, FAD-binding; Identified by match to protein family HMM PF01360; match to protein family HMM TIGR01988. | 0.760 |
| ubiA | MCA2078 | MCA1336 | MCA2078 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Glutaredoxin-related protein; Identified by similarity to GP:19880969; match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.917 |
| ubiA | dsrE | MCA1336 | MCA1331 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Intracellular sulfur oxidation protein DsrE; Identified by similarity to SP:O87896; match to protein family HMM PF02635. | 0.478 |