| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA1339 | MCA1396 | MCA1339 | MCA1396 | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | DnaJ domain protein; Identified by match to protein family HMM PF00226. | 0.764 |
| MCA1339 | MCA2189 | MCA1339 | MCA2189 | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | Cytochrome c family protein. | 0.759 |
| MCA1339 | cbpA | MCA1339 | MCA1727 | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556. | 0.764 |
| MCA1339 | dnaJ | MCA1339 | MCA1855 | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.764 |
| MCA1339 | glnA | MCA1339 | MCA1677 | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.752 |
| MCA1339 | merA | MCA1339 | MCA1340 | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.935 |
| MCA1339 | rpoA | MCA1339 | MCA2347 | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.765 |
| MCA1339 | rpoB | MCA1339 | MCA1066 | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.812 |
| MCA1339 | rpoC | MCA1339 | MCA1067 | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.746 |
| MCA1339 | rpoZ | MCA1339 | MCA2022 | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.746 |
| MCA1396 | MCA1339 | MCA1396 | MCA1339 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | 0.764 |
| MCA2189 | MCA1339 | MCA2189 | MCA1339 | Cytochrome c family protein. | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | 0.759 |
| cbpA | MCA1339 | MCA1727 | MCA1339 | Curved DNA-binding protein; Identified by similarity to SP:P36659; match to protein family HMM PF00226; match to protein family HMM PF01556. | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | 0.764 |
| dnaJ | MCA1339 | MCA1855 | MCA1339 | dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | 0.764 |
| glnA | MCA1339 | MCA1677 | MCA1339 | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | 0.752 |
| glnA | merA | MCA1677 | MCA1340 | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.449 |
| merA | MCA1339 | MCA1340 | MCA1339 | Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | 0.935 |
| merA | glnA | MCA1340 | MCA1677 | Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Glutamine synthetase, type I; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.449 |
| rpoA | MCA1339 | MCA2347 | MCA1339 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Mercuric resistance operon regulatory protein; Identified by similarity to SP:P06688; match to protein family HMM PF00376; match to protein family HMM TIGR02051. | 0.765 |
| rpoA | rpoB | MCA2347 | MCA1066 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.995 |
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