node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCA1344 | apt | MCA1344 | MCA0816 | Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.455 |
MCA1344 | comF | MCA1344 | MCA1124 | Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family. | Competence protein F; Identified by similarity to SP:P31773. | 0.473 |
MCA1344 | guaA | MCA1344 | MCA0290 | Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.417 |
MCA1344 | topA | MCA1344 | MCA2839 | Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.457 |
apt | MCA1344 | MCA0816 | MCA1344 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family. | 0.455 |
apt | comF | MCA0816 | MCA1124 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Competence protein F; Identified by similarity to SP:P31773. | 0.677 |
apt | guaA | MCA0816 | MCA0290 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.991 |
comF | MCA1344 | MCA1124 | MCA1344 | Competence protein F; Identified by similarity to SP:P31773. | Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family. | 0.473 |
comF | apt | MCA1124 | MCA0816 | Competence protein F; Identified by similarity to SP:P31773. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.677 |
guaA | MCA1344 | MCA0290 | MCA1344 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family. | 0.417 |
guaA | apt | MCA0290 | MCA0816 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.991 |
guaA | topA | MCA0290 | MCA2839 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.537 |
topA | MCA1344 | MCA2839 | MCA1344 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family. | 0.457 |
topA | guaA | MCA2839 | MCA0290 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.537 |