| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCA1019 | htpX | MCA1019 | MCA1383 | Conserved hypothetical protein; Identified by similarity to OMNI:NT01MC4376. | Heat shock protein HtpX; Identified by similarity to SP:P23894; match to protein family HMM PF01435; match to protein family HMM PF06509; Belongs to the peptidase M48B family. | 0.619 |
| MCA1225 | htpX | MCA1225 | MCA1383 | Hypothetical protein; Identified by Glimmer2; putative. | Heat shock protein HtpX; Identified by similarity to SP:P23894; match to protein family HMM PF01435; match to protein family HMM PF06509; Belongs to the peptidase M48B family. | 0.619 |
| MCA1308 | htpX | MCA1308 | MCA1383 | Conserved hypothetical protein; Identified by similarity to GP:16502260; match to protein family HMM PF01027; Belongs to the BI1 family. | Heat shock protein HtpX; Identified by similarity to SP:P23894; match to protein family HMM PF01435; match to protein family HMM PF06509; Belongs to the peptidase M48B family. | 0.470 |
| MCA1382 | MCA1384 | MCA1382 | MCA1384 | Hypothetical protein; Identified by Glimmer2; putative. | Methyltransferase, UbiE/COQ5 family. | 0.442 |
| MCA1382 | htpX | MCA1382 | MCA1383 | Hypothetical protein; Identified by Glimmer2; putative. | Heat shock protein HtpX; Identified by similarity to SP:P23894; match to protein family HMM PF01435; match to protein family HMM PF06509; Belongs to the peptidase M48B family. | 0.618 |
| MCA1384 | MCA1382 | MCA1384 | MCA1382 | Methyltransferase, UbiE/COQ5 family. | Hypothetical protein; Identified by Glimmer2; putative. | 0.442 |
| MCA1384 | MCA1386 | MCA1384 | MCA1386 | Methyltransferase, UbiE/COQ5 family. | Hypothetical protein; Identified by Glimmer2; putative. | 0.675 |
| MCA1384 | htpX | MCA1384 | MCA1383 | Methyltransferase, UbiE/COQ5 family. | Heat shock protein HtpX; Identified by similarity to SP:P23894; match to protein family HMM PF01435; match to protein family HMM PF06509; Belongs to the peptidase M48B family. | 0.542 |
| MCA1384 | radA | MCA1384 | MCA1385 | Methyltransferase, UbiE/COQ5 family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.680 |
| MCA1386 | MCA1384 | MCA1386 | MCA1384 | Hypothetical protein; Identified by Glimmer2; putative. | Methyltransferase, UbiE/COQ5 family. | 0.675 |
| MCA1386 | htpX | MCA1386 | MCA1383 | Hypothetical protein; Identified by Glimmer2; putative. | Heat shock protein HtpX; Identified by similarity to SP:P23894; match to protein family HMM PF01435; match to protein family HMM PF06509; Belongs to the peptidase M48B family. | 0.479 |
| MCA1386 | radA | MCA1386 | MCA1385 | Hypothetical protein; Identified by Glimmer2; putative. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.773 |
| MCA2614 | dnaJ | MCA2614 | MCA1855 | Thioredoxin family protein; Identified by similarity to GP:17427791; match to protein family HMM PF00085; match to protein family HMM TIGR01068. | dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.733 |
| MCA2614 | grpE | MCA2614 | MCA1857 | Thioredoxin family protein; Identified by similarity to GP:17427791; match to protein family HMM PF00085; match to protein family HMM TIGR01068. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.803 |
| MCA2614 | htpX | MCA2614 | MCA1383 | Thioredoxin family protein; Identified by similarity to GP:17427791; match to protein family HMM PF00085; match to protein family HMM TIGR01068. | Heat shock protein HtpX; Identified by similarity to SP:P23894; match to protein family HMM PF01435; match to protein family HMM PF06509; Belongs to the peptidase M48B family. | 0.542 |
| dnaJ | MCA2614 | MCA1855 | MCA2614 | dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Thioredoxin family protein; Identified by similarity to GP:17427791; match to protein family HMM PF00085; match to protein family HMM TIGR01068. | 0.733 |
| dnaJ | grpE | MCA1855 | MCA1857 | dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.988 |
| dnaJ | htpX | MCA1855 | MCA1383 | dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Heat shock protein HtpX; Identified by similarity to SP:P23894; match to protein family HMM PF01435; match to protein family HMM PF06509; Belongs to the peptidase M48B family. | 0.659 |
| grpE | MCA2614 | MCA1857 | MCA2614 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Thioredoxin family protein; Identified by similarity to GP:17427791; match to protein family HMM PF00085; match to protein family HMM TIGR01068. | 0.803 |
| grpE | dnaJ | MCA1857 | MCA1855 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.988 |
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