Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MCA1401Arylesterase; Identified by similarity to SP:Q07792; match to protein family HMM PF00657. (226 aa)    
Predicted Functional Partners:
MCA1399
Putative ABC transporter, permease protein; Gene cluster supports this as an ABC transporter component; identified by match to protein family HMM PF02687.
 
 
   0.976
MCA1400
ABC transporter, ATP-binding protein; Identified by similarity to OMNI:VCA0782; match to protein family HMM PF00005.
 
 
   0.966
MCA2227
Hemagglutinin-related protein; Identified by similarity to OMNI:NTL01RSA0540; match to protein family HMM PF05594; match to protein family HMM PF05860; match to protein family HMM TIGR01901.
  
 
 0.791
MCA1402
Conserved hypothetical protein; Identified by similarity to GP:19071499.
       0.773
fabZ
(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
     
 0.713
MCA2186
Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
    0.697
plsY
Conserved hypothetical protein TIGR00023; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
   
  
 0.671
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
     
 0.665
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
      
 0.661
MCA1224
Identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051.
   
  
 0.660
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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