Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA1404Identified by match to protein family HMM PF01565. (578 aa)    
Predicted Functional Partners:
cyp51
Cytochrome P450 51; Identified by similarity to SP:P77901; match to protein family HMM PF00067.
 
 0.988
MCA2872
Identified by match to protein family HMM PF01360.
  
  
 0.890
MCA2873
Squalene cyclase family protein; Identified by similarity to GP:1098635; match to protein family HMM PF00432; match to protein family HMM TIGR01787.
  
  
 0.823
MCA0623
Conserved domain protein; Identified by similarity to GP:11641086.
  
     0.737
MCA1423
Glycosyl transferase, family 25; Identified by match to protein family HMM PF01755.
  
     0.552
MCA1403
Membrane-bound lytic murein transglycosylase; Identified by similarity to SP:P23931; match to protein family HMM PF01464.
       0.464
atpH
ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.
  
 
  0.453
sseA
Mercaptopyruvate sulfurtransferase; Identified by similarity to GP:6009981; match to protein family HMM PF00581.
 
     0.443
MCA2703
Serine protease, trypsin family; Identified by match to protein family HMM PF00089.
  
 
   0.434
tpm
Thiopurine methyltransferase; Identified by similarity to SP:O86262; match to protein family HMM PF05724; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
  
 
   0.425
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.