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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCA1422Hypothetical protein; Identified by Glimmer2; putative. (617 aa)    
Predicted Functional Partners:
MCA1423
Glycosyl transferase, family 25; Identified by match to protein family HMM PF01755.
 
     0.848
MCA1427
Glycosyl transferase, group 2 family protein; Identified by similarity to GP:18159365; match to protein family HMM PF00535.
  
     0.741
MCA1433
Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534.
  
     0.668
MCA1695
Putative cell division protein FtsK; Identified by similarity to SP:P46889; match to protein family HMM PF01580.
    
 
 0.613
MCA1493
Cellulose-binding domain protein; Identified by match to protein family HMM PF00041; match to protein family HMM PF00553; match to protein family HMM PF07631; match to protein family HMM PF07637.
  
 
   0.603
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.541
MCA2477
Conserved hypothetical protein; Identified by similarity to SP:P37512; match to protein family HMM PF03190.
    
   0.529
MCA1424
Putative transporter; Identified by match to protein family HMM PF07690.
       0.528
MCA1440
Response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF07228.
  
   
 0.526
MCA1492
Tat (twin-arginine translocation) pathway signal sequence domain protein; Identified by match to protein family HMM PF07586; match to protein family HMM TIGR01409.
  
     0.501
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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