Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MCA1470Conserved domain protein; Identified by similarity to GP:18496604. (168 aa)    
Predicted Functional Partners:
MCA1469
Putative sigma-E factor regulatory protein; Identified by similarity to SP:P46186.
  
 
 0.988
rpoE
RNA polymerase sigma-30 factor; Identified by similarity to SP:P34086; match to protein family HMM PF04542; match to protein family HMM PF04545; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.978
MCA2656
Conserved hypothetical protein; Identified by similarity to GP:17430238.
  
 
 0.829
mucC
Sigma factor regulator MucC; Identified by similarity to GP:1345103; match to protein family HMM PF04246.
  
  
 0.828
MCA1467
Serine protease, MucD; Identified by similarity to GP:1345104; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family.
  
 
 0.810
sspB
Identified by similarity to SP:P25663; match to protein family HMM PF04386.
    
 
 0.764
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
     
 0.608
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.599
MCA1599
Putative serine protease, MucD; Identified by similarity to GP:1345104; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family.
  
 
 0.589
MCA1619
Trypsin domain protein; Identified by match to protein family HMM PF00089.
  
 
 0.589
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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